Genetic Inheritance and Family Planning

Information about the genetic implications of the Ashkenazi Variant of Wolfram Syndrome, testing locations and more:

Genetic testing is recommended for individuals of Ashkenazi Jewish ancestry to:

  • Identify carriers before starting a family. When both parents are carriers, there is a 25% chance with each pregnancy that their child will be affected by the disorder and a 50% chance that their child will be a carrier.

  • Diagnose individuals experiencing unexplained diabetes, vision loss, or neurological symptoms.

  • Enable early medical intervention to manage symptoms and improve quality of life.

Where to Get Tested

Wolfram Syndrome International Registry & Clinical Study

Testing available at no cost at Washington University in St. Louis.

More information at: wolframsyndrome.wustl.edu

Jewish Genetic Disease Screening Programs

Dor Yeshorim offers confidential genetic screening to help prevent inherited diseases in the Jewish community.

More information at: doryeshorim.org

Local Hospitals & Genetic Counselors

Check with nearby medical centers for genetic counseling and testing services.

More information at: doryeshorim.org